{"id":2305,"date":"2024-06-21T07:20:54","date_gmt":"2024-06-21T07:20:54","guid":{"rendered":"https:\/\/nus.edu.sg\/lsi\/?page_id=2305"},"modified":"2024-06-21T07:21:21","modified_gmt":"2024-06-21T07:21:21","slug":"dr-dennis-hey-hwee-weng","status":"publish","type":"page","link":"https:\/\/www.nus.edu.sg\/lsi\/tissue-engineering\/principal-investigators\/dr-dennis-hey-hwee-weng\/","title":{"rendered":"Dr Dennis Hey Hwee Weng"},"content":{"rendered":"

\"\"Dennis Hey Hwee Weng<\/strong>
\nClinical Director, Department of Orthopaedic Surgery
\nEmail: doshhwd@nus.edu.sg<\/strong><\/a><\/p>\n

\nWhat are your present research interests?<\/strong><\/h3>\n

For clinical research: adult spinal deformity alignment targets and outcomes, endoscopic spine surgery techniques and outcomes, spinal disc arthroplasty techniques and outcomes. For basic science research: intervertebral disc regeneration, hypertrophic ligamentum flavum therapies, sarcopenic spinal changes and treatment.<\/p>\n

\nDo you have a distinctive viewpoint to your research?<\/strong><\/h3>\n

Research should strive towards preserving physiology and disease prevention.<\/p>\n

What do you see as your future research directions?<\/strong><\/h3>\n

Ability to understand, design and administer a wide variety of treatment on adult and degenerative spinal conditions.<\/p>\n


\nDoes your laboratory have a particularly strong research expertise?<\/strong><\/h3>\n

Our laboratory have strong expertise in animal, radiographic and biomechanical work. We have close collaboration with researches that are highly capable in cell therapies and tissue engineering. <\/p>\n


\nRecent Publications<\/strong><\/h3>\n

1. Tan, T. H., Tan, J.-H., & Hey, H. W. D. (2023). Changes in Spinopelvic Parameters Between Standing and Sitting Postures: A Systematic Review and Meta-analysis. Clin Spine Surg. doi:10.1097\/BSD.0000000000001501<\/p>\n

2. Crombie, E. M., Kim, S., Adamson, S., Dong, H., Lu, T. C., Wu, Y., Wu, Y., Levy, Y., Stimple, N., Lam, W.M.R., Hey, H.W.D., Withers, D.J., Hsu, A.L., Bay, B.H., Ochala, J., Tsai, S. Y. (2023). Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity. Journal of Cachexia, Sarcopenia and Muscle, 14(1), 198-213. doi:10.1002\/jcsm.13121<\/p>\n

3. Teo, K. Y. W., Tan, R., Wong, K. L., Hey, D. H. W., Hui, J. H. P., & Toh, W. S. (2023). Small extracellular vesicles from mesenchymal stromal cells: the next therapeutic paradigm for musculoskeletal disorders. CYTOTHERAPY, 25(8), 837-846. doi: 10.1016\/j.jcyt.2023.04.011 <\/p>\n

4. Hey, H. W. D., Lam, W. M. R., Chan, C. X., Zhuo, W.-H., Crombie, E. M., Tan, T. C., Chen, W.C., Cool, S., Tsai, S. Y. (2022). Paraspinal myopathy-induced intervertebral disc degeneration and thoracolumbar kyphosis in TSC1mKO mice model-a preliminary study. SPINE JOURNAL, 22(3), 483-494. doi:10.1016\/j.spinee.2021.09.003 <\/p>\n

5. Hey, H. W. D., Tan, K. -A., Chin, B. Z., Liu, G., & Wong, H. -K. (2019). Comparison of whole body sagittal alignment during directed vs natural, relaxed standing postures in young, healthy adults. SPINE JOURNAL, 19(11), 1832-1839. doi:10.1016\/j.spinee.2019.06.017 <\/p>\n","protected":false},"excerpt":{"rendered":"

Dennis Hey Hwee Weng Clinical Director, Department of Orthopaedic Surgery Email: doshhwd@nus.edu.sg What are your present research interests? For clinical research: adult spinal deformity alignment targets and outcomes, endoscopic spine surgery techniques and outcomes, spinal disc arthroplasty techniques and outcomes. For basic science research: intervertebral disc regeneration, hypertrophic ligamentum flavum therapies, sarcopenic spinal changes andRead More<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":637,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"custompagewithmenu.php","meta":{"footnotes":""},"tags":[52],"class_list":["post-2305","page","type-page","status-publish","hentry","tag-mm-pi-tep"],"_links":{"self":[{"href":"https:\/\/www.nus.edu.sg\/lsi\/wp-json\/wp\/v2\/pages\/2305"}],"collection":[{"href":"https:\/\/www.nus.edu.sg\/lsi\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.nus.edu.sg\/lsi\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.nus.edu.sg\/lsi\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nus.edu.sg\/lsi\/wp-json\/wp\/v2\/comments?post=2305"}],"version-history":[{"count":2,"href":"https:\/\/www.nus.edu.sg\/lsi\/wp-json\/wp\/v2\/pages\/2305\/revisions"}],"predecessor-version":[{"id":2308,"href":"https:\/\/www.nus.edu.sg\/lsi\/wp-json\/wp\/v2\/pages\/2305\/revisions\/2308"}],"up":[{"embeddable":true,"href":"https:\/\/www.nus.edu.sg\/lsi\/wp-json\/wp\/v2\/pages\/637"}],"wp:attachment":[{"href":"https:\/\/www.nus.edu.sg\/lsi\/wp-json\/wp\/v2\/media?parent=2305"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nus.edu.sg\/lsi\/wp-json\/wp\/v2\/tags?post=2305"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}