Dr Paul MACARY

PhD (University of London); B.Sc (Hons) (Glasgow University)
Department of Microbiology and Life Sciences Institute's Immunology Programme

RESEARCH INTERESTS

• Monoclonal antibodies
• Mycobacterium Tuberculosis
• Virus Immunology

RESEARCH ACHIEVEMENTS

• Discovered and characterised a new cellular receptor for the world's most deadly pathogen M.Tuberculosis
• Developed a novel antibody platform for targeting virus-infected cells that may enhance the treatment of Hepatocellular Carcinoma, a type of liver cancer and Nasopharyngeal Carcinoma, a form of throat cancer
• Led the invention of highly innovative anti-lipid antibodies that may help boost the diagnosis of inflammatory and infectious diseases, and is part of a multi-disciplinary project that drew US$7 million
• Helmed a group generating therapeutic antibodies that identify and combat infections arising from the dengue virus, part of a larger project that secured funding of over US$18 million
• Secured competitive research funding of over US$3.5 million over the last five years

RESEARCH STRENGTHS

• Pursues a multi-disciplinary approach by collaborating extensively with scientists and physicians from research institutions, pharmaceutical companies and academia from across Singapore and around the world

PUBLICATION CREDITS

• Over 37 papers published in international journals, with 20 in premium tier ones such as Science, Nature Medicine, Immunity, Blood, Proceedings of the National Academy of Sciences, and over 900 citations received
• Has a current Hirsch index of 16, signifying high scientific productivity and impact
• Authored three manuscripts included in Faculty of 1000 and two covering articles on the BBC

INTERNATIONAL STANDING

• Internationally recognised as a leading researcher in the field of immunology
• Reviewer for leading international journals, such as Blood, Journal of Immunology and FEBS (Federation of European Biochemical Societies) Letters
• Co-founder and non-executive director of the British Stem Cell Registry Ltd
• Founding member and Meetings secretary, Singaporean Society for Immunology

AWARDS AND ACCOLADES

• Excellence in Research, Yong Loo Lin School of Medicine, NUS (2007)
• Office of Life Sciences Young Investigator Award, NUS (2005)
• First prize for Best Research Presentation, Cambridge Institute for Medical Research (2003)

RESEARCH ASPIRATION
"To build one of the world's best antibody-based laboratories for translating antibody candidates into new diagnostics and therapeutics, and to launch a spin-off company from NUS that will lead the way in antibody-based products focussed on Asian disease phenotypes."