
Assoc Prof MELENDEZ,
Alirio J.
Ph.D B. Sc
(University of Glasgow)
MBBS (University of Moscow)
Department of Physiology |
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Young Researcher Award
"A problem is never too big - it can be broken into small parts, making it easier to handle; thus, we can solve any problem. Most importantly, never give up."
Research Interests
- Immunology
- Intracellular Signalling
- Gene Profiling
- Functional Genomics
Research Achievements
- Identification of SPHK1, a novel sphingosine kinase which serves as a potential target for drug development against allergic and inflammatory diseases
- His research on SPHK1 has also paved the way for therapeutic strategies against immune-related diseases such as bronchial asthma
- Has filed five patents, one of which was granted for methods and compositions for screening modulators of lipid kinases
Research Strengths
- Always questioning not just how it works but why it works… and then again why… always looking for an answer without preconceptions wherever it might lead
Publication Credits
- Published extensively in more than 40 publications, including top-tier journals such as the Proceedings of the National Academy of Sciences USA, Current Biology, Blood, Journal of Immunology and Journal of Biological Chemistry
International Standing
- Highly regarded as a scientist internationally and sits on advisory panels of international biopharmaceutical companies in the United Kingdom and India
- Serves as a reviewer for top tier publications such as the Annals of the Rheumatic Diseases and FASEB journal
- Serves as a reviewer for local and international grant awarding bodies such as the Biomedical Research Council, National Medical Research Council and the Dutch Agency for Science and Technology Research
Awards and Accolades
- BMRC Young Investigator Award (2002)
Research Aspiration
To better understand the immune system in order to control it when necessary and to harness its full potential.
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