HBR Forms

List of HBR Forms for Download 

1) Please read Submission Instructions and Guidelines for help with filling in the forms.

2) These forms are subject to changes as the Human Biomedical Research Act is implemented in phases.

3) The forms are in Microsoft Word format.

4) Please note that all forms and guidelines are only accessible via NUS network for NUS staff and students. If you are off-campus, please connect to VPN first before accessing the the files. VPN link: https://webvpn.nus.edu.sg/dana-na/auth/url_52/welcome.cgi  

For New Applications




Full / Expedited Review - Revised
Study Protocol (for use in Exemption Applications)
e-Declarations (Commercial Cell Lines and Human Biological Materials Only) - Revised
Determination of HBR
HBR Self-Checklist for PI
For Approved Protocols




Protocol Amendment Form
Study Status Report (for Windows user)
Study Status Report (for Mac users)  Download
Serious Adverse Event (SAE) Form - Revised
Guidelines on SAE Form and Notification of SAE
and Suspected Offence/Contravention of HBRA - Revised
Protocol Non-Compliance / Deviation Form - New  Download
Guidelines on Protocol Non-Compliance/ Deviation Form - New  Download
Report of Expected/ Unexpected Events Form - New  Download
Guidelines on Report of Expected/ Unexpected Events Form - New Download
MOH Contravention Form - Revised Download
MOH Unexpected Serious Adverse Event Form - New Download
Human Sample Types Template

Human Sample Types Template (for non-commercial cell lines)

List of PI and Co-Investigators
HOD Assessment


Please submit all forms to:

The Secretariat
National University of Singapore
Institutional Review Board
Clinical Research Centre (Blk MD 11)
Level 5 #05-09
10 Medical Drive
Singapore 117597


Note: Guidelines and Forms are accessible to NUS researchers only. 
For non-NUS researchers, please contact