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Register of Safety & Health Regulations Applicable to Laboratories

This table provides an overview of national safety and health regulations and internal standards applicable to NUS.
Staff are kindly advised to consult their respective Faculty Workplace Safety and Health Officers for more information. Information about OSHE’s programmes and services can be found at the following website (

You may refer to the Regulated Chemical Identifier in assisting for the regulated chemicals that you possess and uses in your laboratories.

Act/Regulation Regulatory Body Key Requirements Applicable to Staff Licenses/Permits Required
1 Workplace Safety & Health Act
a WSH (General Provision) Regulations 2006
b WSH (First Aid) Regulations 2006
c WSH (Incident Reporting) Regulation 2006
d WSH (Risk Management) Regulation 2006


Provides general requirements on safety and health issues related to the workplace such as 
- Use of hazardous materials
- Use of pressure vessels

Provides requirements of first-aid facilities (first-aid box,
first-aiders) in the workplace
Provides requirements for notification and reporting of death and dangerous occurrences and reporting of injuries and occupational diseases
Provides requirements of risks assessments / management to be carried out for all lab-based activity
For more details
Autoclaves and pressure vessels must be inspected frequently by a professional engineer
2 Petroleum And Flammable Materials (PFM) Regulations
Regulates import, transport and storage of petroleum and flammable materials
List of chemicals falling under regulation must be stored within
maximum permissible limit and storage requirements stipulated by SCDF
For NUS storage limits of
PFMs, refer to 
For More Information
Inventory declaration of PFM in a prescribed NUS format to OSHE
3 Chemical Weapons Convention
Chemical Weapons (Prohibition) Act Storage, Use and Disposal

Singapore National Authority for the Chemical Weapons Convention
Regulates chemicals classified under chemical weapons
  The list of chemicals can be
All chemicals must be stored, used and disposed in accordance to the requirements of the regulations
These chemicals must not be bought or used without approval and license applied for through OSHE
  A copy of the act can be
NA(CWC) licence
Notify NUS OSHE on CWC quantities
4 Poisons Act


Regulates substances classified under Poisons (potent medical
The list of poisons can be found
All poisons must be kept under lock and key in a designated poison cupboard
Records of toxins and flammable chemicals must be kept
Poisons licence, held by faculty
5 Environmental Protection & Management Act
a Environmental Pollution Control (Hazardous Substances)
b Environmental Pollution Control (Ozone Depleting Substances)


Regulates purchase and use of toxic and environmentally hazardous chemicals.
  The list of chemicals can be found
  For quantity limits, please visit
All hazardous chemicals must not be bought or used without approval and license applied for through Faculty Safety and Health Officers
For more information
Hazardous substance permit, held by faculty
6 Environmental Public Health Act
a Environmental Public Health (General Waste Collection) Regulations
b Environmental Public Health (Toxic Industrial Waste) Regulations



Regulates disposal of toxic and environmentally hazardous chemicals
Only licensed waste collector must be engaged to collect hazardous waste generated
All generated toxic & hazardous waste must be treated & properly packed in specified containers with appropriate labeling
  For more information
NUS staff to only engage licenced waste collectors
7 Sewerage & Drainage Act
  Sewerage and Drainage (Trade Effluent) Regulations


Regulates the discharge of waste water into public sewers
The regulations specify allowable limits for trade effluent
discharge into the public sewer
The requirements of the regulations can be found
NUS staff and students not to dispose hazardous materials into the sewer
8 Misuse of Drug Regulation


Provide for possession, supply, import, manufacture and record keeping of controlled drugs
Serves to regulate the legitimate use of controlled drugs by
For the list of controlled drugs and more information on this act
License to import and export controlled drugs
9 Radiation Protection Act
Radiation Protection (Non-ionizing) Regulations
Radiation Protection (Ionizing Radiation) Regulations
Radiation Protection (Transport of Radioactive Materials)


Specifies requirements for use and storage of ionizing radioactive materials/ irradiating apparatus and non-ionizing equipment such as ultraviolet sunlamps, microwave ovens, medical and industrial ultrasound apparatus, magnetic resonance imaging (MRI) apparatus,
entertainment lasers and high power lasers
Research personnel using any radioactive material/irradiating equipment as well as non ionizing equipment and laser must be adequately trained
Research personnel working with ionizing and/or non ionizing
radiation must be medically certified & monitored
  For more information
  Singapore Statues Online
Different classes of licenses - competency level, use,
transportation or equipment based
10 Biological Agents and Toxin Act


Regulate the possession, use, import, transfer and transportation of biological agents (BAs) and toxins that are known to be hazardous to human health in Singapore
Approval is required for the
possession, import, handling and transportation of scheduled
biological agents and toxins
Proper decontamination is
required for all waste prior to disposal
  The list of Biological agents and toxins can be found here
Agent specific license issued by MOH to PIs
11 WHO guidelines for Biosafety


National guidelines for biosafety adopted by MOM
The guidelines are defined in the WHO Laboratory Biosafety Manual, 3rd edition
A copy of the manual can be found


12 GMAC Guidelines


National guidelines covering research and commercial release of agriculture-related Genetically Modified organisms (GMOs):

Singapore Biosafety Guidelines for Research on Genetically Modified Organisms (GMOs)
Singapore Guidelines on the Release of
Agriculture-Related Genetically Modified Organisms (GMOs)
GMAC endorsement is required for importation of GMOs or
GMO-derived products prior to import permit approval by the relevant regulatory agencies (e.g. the MOH or AVA)
The guidelines are available
GMAC notification/ approval required for conducting medium to high risk projects and for importation of GMOs or GMO-derived products
13 Animals and Birds Act
Regulates Veterinary biologics* including pathogens

The list of regulated pathogens known as AVA's 'select list' can be found here

Please note that this list is not exhaustive and if any researcher wants to use a potential animal pathogen that is not listed here OSHE / AVA should be consulted

This act also regulates animals, including fish and birds and animal tissues

For veterinary biologics including pathogens a license to possess and import license is required

PIs need to obtain individual licenses from AVA which are agent / consignment specific before using / importing any veterinary biologic

For inquires related to import of animals and animal tissues please contact comparative medicine (CM)

*Veterinary biologics means any viruses, serums, toxins, and analogous products of natural or synthetic origin, including genetically modified organisms, diagnostics, antitoxins, vaccines, live micro-organisms, killed micro-organisms, and the antigenic or immunizing component of micro-organisms intended for use in the diagnosis, treatment, or prevention of diseases of animals and birds, or for purposes of research in animals or birds

14 Guidelines, Arms and Explosives (Amendment) Act, Chap 13


Regulate the use of 15 chemicals that are classified as Explosive
precursors. Previously 13 of the precursors were regulated by NEA
The applicant will be the one directly involved in the handling of the explosive precursors
It is a requirement that the holder of the license has relevant experience and knowledge in handling the explosive precursors and a
register book shall be kept and maintain on the data of the
explosive chemical

For more information
Licence is held at the faculty level

Regulatory body:
1 GMAC - Genetic Modification Advisory Committee ( )
2 HSA - Health Sciences Authority ( )
3 MOH - Ministry of Health (
4 MOM - Ministry of Manpower ( )
5 NACWC - National Authority for the Chemical Weapons Convention (
- National Environmental Agency ( )
- Centre for Radiation Protection & Nuclear Science
7 PUB - Public Utilities Board ( )
8 SCDF - Singapore Civil Defence Force ( )
9 AVA - Agri-Food & Veterinary Authority of Singapore (
10 SPF - Singapore Police Force (




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