NUS Graduate School for Integrative Sciences and Engineering

Toshio SUDA

Supervisor
Research Areas
Brief Description of Research
1. Hematopoietic stem cell niche biology.
2. Differential regulation of normal hematopoietic and leukemic stem cells
3. Stem cells expansion
4. Humanized model for stem cell niche

 

1. Manipulation of the hematopoietic stem cell (HSC) niche for the ex vivo expansion of HSCs.
2. Elucidation of niche involvement in the pathophysiology of hematopoietic malignancies along with the identification of molecular targets of diseases.
3. Identification of stemness-related cis-regulatory elements.
4. Establishment of human stem cell niche in immunodeficient mouse.