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Caroline LEE

Supervisor	Research focus	Detailed Research Projects
Caroline LEE Personal Website Research Link	1. Cancer Functional Genomics. 2. Population genetics / Pharmacogenetics.	1. Molecular elucidation of proteins that interact with FAT10 in the carcinogenesis process. 2. Identification and functional characterization of mutations and/or polymorphisms in FAT10 gene to elucidate the role of these mutations/polymorphisms in the carcinogenesis process. 3. Elucidation of gene regulation mechanism in Cyr61 to understand the downregulation of its expression in hepatocellular carcinoma. 4. Genetic and genomic approaches to predicting drug response in advanced colorectal cancer patients. 5. Identification of functionally-important polymorphisms in drug response genes using large-scale computational and experimental strategies.

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