1. | Drug Development |
2. | Cancer Research |
3. | Bioimaging |
4. | Catalysis & Biocatalysis |
5. | Bioinorganic Chemistry |
Our research interest lies at the interface of chemistry and biology, in the study and development of metallocomplexes for targeted cancer therapy. Our work focuses mainly on Pt- and Ru-based complexes as non-classical therapeutic agents and elucidating their modes of action. We are also actively pursuing fluorescence probes that would allow us to investigate these compounds in live cell models. Our 4 broad areas of research are:
1) Developing the chemistry of platinum(IV) carboxylates as anticancer prodrug complexes
2) Fluorescence probes for the investigation of cisplatin and its parent platinum(IV) prodrug complexes
3) Metallocomplexes as Immuno-Chemotherapeutic agents
4) Coordination-directed 3-component Assembly of ruthenium-arene complexes for drug discovery