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2007 2006

   
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BREAKTHROUGHS ACHIEVED BY NUS RESEARCHERS IN THE REVIEW YEAR From the research labs of NUS have emerged in the year breakthroughs and new discoveries that are likely to affect the thinking and practices of conventional wisdom. Below are some examples drawn from the broad scope of NUS’ research portfolio:

  • Discovery that foetal stem cells are able to cross the blood-brain barrier into the mother’s brain during pregnancy and differentiate into different neural cells highlighted new possibilities in non-invasive cell-based therapies for neurodegenerative diseases. The research is a collaborative effort between NUS, Singapore General Hospital and the Institute of Molecular and Cell Biology. Its findings were published in Stem Cells (August 2005).

  • Identification and characterisation of Juxtanodin, a novel protein of the nervous system, that could pave the way for developing more effective ways of treating neurological disorders such as multiple sclerosis and schizophrenia. The findings were published in the Proceedings of the National Academy of Sciences of the USA (July 2005).

  • Discovery of the world’s smallest vertebrate which presents an interesting model for the study of its genome for acid tolerance, resistance to decalcification and its position in the phylogenetic scale.

  • Discovering that the gene RUNX3 is not functioning in about 80 per cent of gastric cancer. The finding has important implications in screening drugs for therapeutic purposes and was published in Cancer Research (September 2005).

  • Establishing a class of new schemes by using quantum physics to secure encryption more systematically and efficiently.

  • Developing electromagnetic meta-materials (EM3) with properties not found in naturally occurring materials. This new artificial material is expected to provide new functionalities and enhancements to future optical and optoelectronics devices.
     
   

CAMPUS INSPIRED, GLOBAL BRAND Review of entrepreneurship NUS contributes to a better tomorrow when the new technologies and innovations developed through its research are transplanted into the real world as applications that can be used by communities everywhere.

     
 

To facilitate the movement from laboratory to boardroom, the University continues to actively promote a culture of entrepreneurship in its community of students, faculty and alumni, through education, research, funding and incubation of start-ups. Enrolment in entrepreneurship-related courses jumped 116 per cent over a one-year period from the last academic year 2004-2005. At NUS Incubator Centre, alumni comprise the largest cluster of NUS stakeholders utilising the facility.

The University won in the year the Enterprising Agency Award and Innovator Award presented by the Prime Minister’s Office for its effort in championing radical innovations and taking the lead in piloting trials. Presented under Enterprise Challenge 2005 , the award was for the development of a novel resorbable bioscaffold by researchers from the Faculty of Dentistry working in collaboration with industry partner, Rapid Tech Pte Ltd. The bioscaffold is able to biodegrade within six months without compromising the strength and support that are needed in the crucial few months of implantation to allow bones to regenerate. Funds from the award will allow the team to translate the technology into clinical trials paving the way for more successful implant and reconstructive surgeries.

In the build up of its entrepreneurial dimension, the University rationalised in the year the various activities of licensing, intellectual property management and technology transfer under the umbrella of the newly-formed Industry Liaison Office.

The Office took off to a propitious start with the launch of NUS-developed dengue fever diagnostic kits by Veredus Laboratories Pte Ltd, a local medical diagnostics company. Two master research agreements were also signed with General Motors and Sony Electronics ( Singapore).

Following the success of the University’s Start-Up@Singapore Business Plan Competition which has spawned more than 50 companies since its inception in 1999, the University followed through with another competition to add impetus to the cultivation of an entrepreneurial outlook amongst its stakeholders. Organised jointly with the Agency for Science, Technology and Research (A*STAR), the Idea to Product Competition (I2P) was modelled after the University of Texas’ I2P International Competition and was the first to be held in Asia.

Students were particularly active in starting up new enterprises in this period. Of the 19 start-ups that took off in the year, 16 were student ventures. One of the most promising is based on a breakthrough by a multi-disciplinary team of engineering and dentistry graduate students. Together with the Centre for Scientific Enterprise, UK, they have set up Biomers Pte Ltd. The medical device company’s first products are the world’s first translucent orthodontic wires with no compromise to their efficacy. Clinical studies are set to begin in academic year 2006– 2007 and the results will be used to secure the approval of the Food and Drug Administration for sale of the company’s products in the US.

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