Research Appointment

Cell and Tissue Culture Laboratory

Applications are invited for the position of a Post-doctorate Research Fellow to work on the project supported by Academic Research Fund, the Ministry of Education, Singapore: Production of Bone Cells from Human Embryonic Stem (ES) Cells - Potential for Transplantation Therapy and Drug/Biomaterial Screening. The collaboration of the project is between Faculty of Dentistry, Faculty of Science, Faculty of Medicine, NUS, and Genome Institute of Singapore. This research is to stimulate and direct the differentiation of human ES cells toward osteogenic cell lineages. The osteogenic cell lineages from human ES cells would be an ideal unlimited source of human cells for many purposes such as (1) the study of development and gene control of human osteogenic cell lineages, osteogenesis, bone regeneration, remodeling and reconstruction; (2) gene/protein delivery therapy to cure bone diseases; (3) cell-injection therapy for bone repair; (4) cell transplanting based bone reconstruction including bone tissue engineering; and (5) the development of cytotoxicity/genotoxicity screening tests for bone related biomaterials and drugs. The following techniques are utilised: culture of ES cells, stimulation of osteogenic differentiation, co-culture of ES cells and primary osteoblasts, in vivo implantation, histochemistry, histology, immunocytochemistry, RNA extraction and RT-PCR, DNA microarray, confocal microscopy, Micro computed tomography, SEM/TEM, etc.

Qualifications & Experience

• Ph.D. or equivalent in Life Sciences, with experience and competence documented by solid quality publications.
  
• Show strong interest in the above stated areas of research and development.
  
• Good oral and written communication skills, and will be expected to help the Principle Investigator of the project to supervise support staff and students at undergraduate and graduate levels in a team to work on a group of projects in the laboratory.
  
• Good analytical and inter-personal skills to work with other teams in a multi-disciplinary laboratory.

Remuneration

• Attractive compensation will commensurate with qualifications and experience (under NUS guideline).
  
• Attendance of International conferences will be supported.
  
• Leave and limited medical benefits will be provided.

Application

Interested candidates please e-mail your full resume in confidence, stating date of availability to dencaot@nus.edu.sg and/or send a hard copy to:

Asst Prof Cao Tong
Principle Investigator
Cell and Tissue Culture Laboratory
Faculty of Dentistry
5 Lower Kent Ridge Road
Singapore 119074
Fax: (65) 6778-5742
E-mail : dencaot@nus.edu.sg
(We regret that only shortlisted candidates will be notified.)

Further information

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